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. 2013 Jan 17;6(2):137–143. doi: 10.1093/ckj/sfs183

Table 1.

Factors associated with QT tract abnormalities in the general population and CKD patients

Genetic factors
 Defects of the myocardial sodium and potassium channels
 Defects of the myocardial potassium channels
 Environmental factors
Electrolytes shift during HD:

  •  Low potassium concentration in the dialysis bath (2 mmol/L)

  •  Low calcium concentration in the dialysis bath (1.25 mmol/L)

  •  High bicarbonate concentration in the dialysis bath (34 mmol/L)

Use of calcium-containing phosphate binders
Excessive Mg intake
Drugs

  •  Antiarrhythmic

  •  Antibiotics

  •  Antihistaminic

  •  Psychotropic

  •  Antiepileptic

  •  Antiviral

  •  Antihypertensive

Comorbidities
Extensive vascular calcification (coronary artery calcification)
History of ischaemic heart disease
LVH
Central nervous system injury