Pedigree of the Iranian family with Usher syndrome type IIC. Black symbols indicate individuals with USH2C, open symbols represent unaffected individuals. The grey symbols indicate individuals with a nonsyndromic form of hearing loss. On the left, the markers are listed which were analysed to define the candidate region. The haplotypes for all analysed individuals are shown, with the linked haplotype indicated by a box. VLGR1 is located between markers D5S618 and D5S1462. Individual V:2 and V:14 were thought to be affected, based on anamnestical data, but they were not fully examined.