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. 2015 May 1;21(5):321–354. doi: 10.1089/tmj.2015.0029

Table 6.

Tele-ophthalmology Programs and Systems

    TELE-OPHTHALMOLOGY PROGRAM VALIDATION CATEGORY LEVELS
INTERNATIONAL CLASSIFICATION LEVEL OF DR ETDRS LEVEL OF DR CATEGORY 1 SYSTEMS IDENTIFY CATEGORY 2 SYSTEMS IDENTIFY CATEGORY 3 SYSTEMS IDENTIFY CATEGORY 4 SYSTEMS IDENTIFY
No apparent DR DR absent No or minimal DR Patients without sight-threatening DR or DME No DR, NPDR, early and high-risk DR, and DME for follow-up and treatment strategies All levels of DR or DME; photographs match, exceed, or can replace ETDRS photographs in any clinical or research program.
Mild DR Very mild NPDR        
Moderate NPDR Moderate NPDR More than minimal DR—but patients require additional screening      
Severe NPDR Severe NPDR, very severe NPDR   Patients with sight-threatening DR, NPDR, and PDR    
PDR PDR, High Risk PDR, Very Severe or Advanced PDR        

DME, diabetic macular edema; DR, diabetic retinopathy; ETDRS, Early Treatment Diabetic Retinopathy Study (30°, stereo seven-standard field, color, 35-mm slides as reference); NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.