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. 2015 Apr 2;12:9. doi: 10.1186/s12987-015-0004-z

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© Ivkovic et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Illustration of DW-MRI changes location. Left: Regional changes in mean diffusivity within T1-hypointensities, before versus after the acetazolamide treatment for patient ACZ_3. Right: Changes in isotropic water fraction, within white matter, on the same brain slice. Red indicates decrease in the isotropic water fraction, blue indicates increase.