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. 2015 May 15;5:10247. doi: 10.1038/srep10247

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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In the simulated populations (AFR, ASN, AMR, EUR), each of which has 100 thousand individuals, the Hamming distances and duality frequencies are generated by both the optimized sets of SNPs and the random sets of SNPs. The SNP numbers range from 20 to 50. The different populations are represented by different colors, and the lines stand for the optimized sets of SNPs and the asterisks stand for the average values of the random sets of SNPs.