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. 2015 May 15;5:95. doi: 10.3389/fonc.2015.00095

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Copyright © 2015 Parker, Vella, Xavier, Amirkhani, Parker, Cebon and Molloy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phosphorylation rate analysis. (A) Correlation of metrics for P-site effect with protein abundance effect measured between drug sensitive and resistant cell populations. Green = P-site effect twofold > protein effect. Red = P-site effect twofold < protein effect. Log₂ intensity of P-sites and total protein for key cytoskeletal regulators (B) myosin and destrin, (C) guanidine exchange factors (11, 40, and 1), and (D) microtubule-associated proteins 1A and 1B analyzed using a Student’s t-test (error bars are SD).