Table 1.
1-D gene enrichment analysis.
| KEGG pathway name | Proteinsa | Medianb | Benj. Hoch. FDR |
|---|---|---|---|
| Mismatch repair | 14 | 0.50 | 3.4E-03 |
| DNA replication | 24 | 0.34 | 1.3E-04 |
| Nucleotide excision repair | 21 | 0.26 | 4.6E-04 |
| Cell cycle | 40 | 0.22 | 3.5E-04 |
| Huntington’s disease | 97 | −0.37 | 3.3E-03 |
| Oxidative phosphorylation | 73 | −0.40 | 7.2E-04 |
| Alzheimer’s disease | 87 | −0.41 | 3.3E-03 |
| Parkinson’s disease | 76 | −0.41 | 3.0E-04 |
| Glycolysis/gluconeogenesis | 34 | −0.48 | 4.6E-03 |
| Ribosome | 72 | −0.52 | 1.2E-08 |
| Cardiac muscle contraction | 25 | −0.55 | 6.6E-04 |
| Peroxisome | 30 | −0.59 | 2.9E-03 |
| Aminoacyl-tRNA biosynthesis | 30 | −0.60 | 3.5E-04 |
| Fatty acid metabolism | 24 | −0.60 | 1.6E-03 |
| Citrate cycle (TCA cycle) | 27 | −0.61 | 2.2E-03 |
| Valine, leucine, and isoleucine degradation | 26 | −0.62 | 4.1E-04 |
| Pyruvate metabolism | 27 | −0.63 | 1.4E-03 |
| PPAR signaling pathway | 22 | −0.67 | 2.6E-03 |
| Tryptophan metabolism | 14 | −0.75 | 3.3E-04 |
aNumber of proteins annotated with the KEGG pathway.
bMedian log2 fold change for proteins annotated within the KEGG pathway.