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. 2015 Mar 18;113(9):3172–3185. doi: 10.1152/jn.00113.2015

Table 1.

Comparison of biophysical properties between human Nav1.8 and rat Nav1.8

Activation
Fast Inactivation
V1/2,act, mV n V1/2,fast, mV Offset n Ramp Current n Persistent Current n
Rat Nav1.8 −6.21 ± 1.62 17 −35.53 ± 1.6 2.25 ± 0.42% 16 12.1 ± 2.1% 9 4.2 ± 0.4% 17
Human Nav1.8 −11.12 ± 1.76* 17 −31.86 ± 0.58* 9.2 ± 1.61%*** 15 21.9 ± 1.1%** 12 12.3 ± 1.3%*** 17

Values are means ± SE. V1/2,act, V1/2,fast, potential at which activation or fast inactivation is half-maximal.

*

P < 0.05,

**

P < 0.01,

***

P < 0.001.