Table 1.

Correlation between KPNA2 expression and clinicopathologic characteristics of UTUC patients after RNU

		KPNA2 immunoreactivity
Variable	Case No.	Low (N = 101)	High (N = 75)	P *
Sex				0.038
Male	78	48	30
Female	98	53	45
Age (y)				0.95
≥70	84	48	36
<70	92	53	39
BMI (kg/m2)				0.26
>27	37	24	13
27-22	81	46	35
<22	58	31	27
Tumor size (cm)				0.46
≥3.5	81	41	40
<3.5	95	60	35
T stage				<0.001
Ta-T1	61	48	13
T2	70	36	34
T3	42	17	25
T4	3	0	3
Pathologic lymph node stage				0.25
N0	168	98	70
N+	8	3	5
G grade				<0.001
G1	3	3	0
G2	105	77	28
G3	68	21	47
eGFR (ml/min/1.73 m2)#				0.83
≥60	77	48	29
60-15	90	49	41
<15	9	4	5
Hydronephrosis				0.24
Absent	70	46	24
Present	106	65	41
Location				0.30
	81	50	31
Renal pelvis Proximal	6	5	1
Middle	17	9	8
Distal ureter	52	26	26
Multiple	20	11	9
Side				0.95
Left	82	49	33
Right	94	52	42
Tumor multiplicity				0.99
Single tumor focus	121	69	52
Multiple tumor foci	55	32	23
Tumor configuration				0.53
Papillary	140	82	58
Nonpapillary	36	19	17

*Mann–Whitney test for the comparison between two groups or Kruskal-Wallis test for more than two groups.

# Estimated glomerular filtration rate (eGFR) was calculated using the re-expressed Modification of Diet in Renal Disease (MDRD) formulas for the Chinese population.