Skip to main content
. Author manuscript; available in PMC: 2015 May 15.
Published in final edited form as: J Nucl Med. 2010 Jan;51(1):121–129. doi: 10.2967/jnumed.109.066126

FIGURE 1.

FIGURE 1

Pharmacochemical properties of Abl inhibitor for direct imaging. (A) Chemical structure of 124I-SKI230. (B) Time course of binding of 131I-SKI230 to K562 cells (solid line and ■ = on rate; dotted line and ○ = off rate). (C) Saturation binding of SKI230 to K562 cells (inset Scatchard transformation). (D) Displacement binding of 131I-SKI230 to K562 cells by SKI230 (solid line and ■) and imatinib (dotted line and ○).