Table 2.
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Conditions: Substrate 1 (0.1 mmol), Pd(OAc)2 (10 mol%), AgOAc (0.2 mmol), p-Tol–I (0.15 mmol), Ligand (20 mol%), HFIP (1.0 mL), 75 °C, 24 h.
The yields were determined by 1H NMR analysis of the crude product using CH2Br2 as an internal standard. The mono:di ratio was determined by 1H NMR.