Skip to main content
. Author manuscript; available in PMC: 2016 Mar 11.
Published in final edited form as: J Am Chem Soc. 2015 Mar 3;137(9):3338–3351. doi: 10.1021/ja512690x

Table 3.

Substrate Scope of Aryl Iodides of Mono-Arylationa,b

graphic file with name nihms688285f11.jpg
a

Conditions: Substrate 1 (0.1 mmol), Pd(OAc)2 (10 mol %), AgOAc (0.2 mmol), Ar–I (0.15 mmol), 2-picoline (20 mol%), HFIP (1.0 mL), 75 °C, 24 h.

b

Isolated yields are shown.

c

Ar–I (0.3 mmol).

d

After C–H activation, the reaction mixture was subjected to PhI(OAc)2 (0.1 mmol), MeOH (1 mL), 80 °C, 3 h. Yields for two steps.