Table I.
Changes in the mean number of pyramidal neurons of the hippocampal CA1 region in the ischemia-operated and IPC + ischemia-operated gerbils.
| Time after IR | Ischemia-operated group
|
IPC + ischemia-operated group
|
||
|---|---|---|---|---|
| NeuN+ | F-J B+ | NeuN+ | F-J B+ | |
| Sham | 354±14.14 | 0 | 344±12.36 | 0 |
| 1 day | 364±16.88 | 0 | 351±15.66 | 0 |
| 2 days | 359±13.65 | 5±3.72a | 357±16.71 | 0 |
| 5 days | 38±14.36a,b | 141±15.77a,b | 331±15.65a,b | 17±6.74a,b |
The mean number of NeuN+ and F-J B+ cells was counted in a 200×200 μm2 of the stratum pyramidale of the CA1 region following ischemia-reperfusion (I-R) (n=7 per group;
a
P<0.05, indicates significant difference from the corresponding ischemia-sham-operated group,
b
P<0.05, indicates significant difference from the respective former group). IPC, ischemic preconditioning; IR, ischemia-reperfusion; NeuN+ neuronal nuclei positive; F-J B, Fluoro-Jade B.