Table II.
Semi-quantification of the immunoreactivity of KYNA in pyramidal cells in the hippocampal CA1 and CA2/3 regions in the ischemia-operated and IPC + ischemia-operated groups.
| Antibody | Region | Groups | Category | Time after ischemia-reperfusion
|
|||
|---|---|---|---|---|---|---|---|
| Sham | 1 day | 2 days | 5 days | ||||
| KYNA | CA1 | Ischemia | CSP | + | ++ | ± | ± |
| IPC + ischemia | CSP | + | ++ | ++ | ++ | ||
| CA3 | Ischemia | CSP | + | + | + | + | |
| IPC + ischemia | CSP | + | + | + | + | ||
Immunoreactivity was scored as −, ±, + or ++, representing no staining, weakly positive, moderate or strong, respectively. CSP, cells in the stratum pyramidale; IPC, ischemic preconditioning; KYNA, kynurenic acid.