Figure 8.

Effects of transfection with activating transcription factor 3 (ATF3) siRNA and of cisplatin on the relative mRNA levels of ATF3, maspin and matrix metalloproteinase 2 (MMP2). (A and C) The mRNA levels of ATF3 and MMP2 were consistent in each experimental group, with the relative mRNA expression of in the untreated control group and the control-siRNA group being the highest, followed by the the cisplatin group; the ATF3-siRNA group had much lower levels, and the ATF3-siRNA + cisplatin group the lowest. (B) The relative mRNa expression of maspin in the ATF3-siRNA group was highest, followed by the untreated control group and the control-siRNA group; the cisplatin group had much lower levels, and the ATF3-siRNA + cisplatin group the lowest.