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Voxel-based statistical group comparison (non-carriers > carriers). In non-carriers of the apolipoprotein (APOE) ε4 allele, lesions were more likely to occur at the horns of the lateral ventricles and the splenium of the corpus callosum than they were in carriers at a whole-brain permutation-based threshold of P < 0.05 (z = 3.0).
