Table 4.
TGF-β1 C-509T and TGFBR2 G-875A polymorphisms and lung adenocarcinoma risk, stratified by fuel smoke exposure
| Polymorphism | Exposure to fuel smoke | Non exposure to fuel smoke | P interaction | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | OR adg | 95% CI | P | Cases | Controls | OR adg | 95% CI | P | ||
| TGF-β1 C-509T | 0.685 | ||||||||||
| CC | 21 | 17 | 1.0 | 57 | 62 | 1.0 | |||||
| CT | 43 | 47 | 0.706 | 0.325-1.533 | 0.378 | 95 | 115 | 0.886 | 0.564-1.394 | 0.601 | |
| TT | 14 | 21 | 0.501 | 0.195-1.289 | 0.152 | 42 | 51 | 0.883 | 0.512-1.523 | 0.601 | |
| CT/TT | 57 | 68 | 0.642 | 0.305-1.353 | 0.244 | 137 | 166 | 0.885 | 0.578-1.356 | 0.576 | |
| TGFBR2 G-875A | 0.922 | ||||||||||
| GG | 61 | 57 | 1.0 | 121 | 145 | 1.0 | |||||
| GA | 15 | 24 | 0.594 | 0.280-1.257 | 0.173 | 65 | 78 | 0.987 | 0.655-1.488 | 0.951 | |
| AA | 2 | 4 | 0.465 | 0.082-2.648 | 0.388 | 8 | 5 | 1.901 | 0.606-5.963 | 0.271 | |
| GA/AA | 17 | 28 | 0.574 | 0.282-1.167 | 0.125 | 73 | 83 | 1.043 | 0.700-1.553 | 0.837 | |
Abbreviation: OR adg age-adjusted odds ratio, CI confidence interval.