Table 1.
Clinical characteristics of patients with CAVD and controls
| Variable | Controls (n=164) | Patients with AVSc (n=164) | Patients with AVS (n=96) | P 1 | P 2 |
| Age (year) | 73.2±7.5 | 73.2±7.5 | 74.1±8.0 | 1.000 | 0.402 |
| Men | 107 (65.2%) | 107 (65.2%) | 59 (61.5%) | 1.000 | 0.540 |
| Diabetes mellitus | 56 (34.1%) | 50 (30.5%) | 29 (30.2%) | 0.479 | 0.962 |
| Hypertension | 128 (78.0%) | 126 (76.8%) | 72 (75.0%) | 0.792 | 0.738 |
| Smoking (current or past) | 42 (25.6%) | 40 (24.4%) | 21 (21.9%) | 0.799 | 0.644 |
| Hypercholesterolemia | 51 (31.1%) | 53 (32.3%) | 25 (26.0%) | 0.812 | 0.287 |
| Total cholesterol (mmol/L) | 3.77±1.06 | 4.07±0.94 | 4.17±1.07 | 0.007 | 0.396 |
| HDL-cholesterol (mmol/L) | 1.18±0.33 | 1.18±0.30 | 1.19±0.27 | 0.933 | 0.761 |
| LDL-cholesterol (mmol/L) | 2.27±0.85 | 2.45±0.81 | 2.54±0.86 | 0.040 | 0.402 |
| Triglycerides (mmol/L) | 1.51±0.92 | 1.51±0.90 | 1.45±0.74 | 0.963 | 0.586 |
| Body mass index (kg/m2) | 24.2±2.6 | 24.4±3.5 | 23.8±3.4 | 0.458 | 0.120 |
| Glomerular filtration rate (ml/min per1.73 m2) | 78.1±13.8 | 78.2±14.3 | 75.3±15.8 | 0.940 | 0.131 |
| Coronary artery disease | 91 (55.5%) | 96 (58.5%) | 50 (52.1%) | 0.577 | 0.312 |
| 1-vessel | 52 (57.1%) | 55 (57.3%) | 28 (56.0%) | 0.724 | 0.466 |
| 2-vessel | 30 (33.0%) | 34 (35.4%) | 17 (34.0%) | 0.577 | 0.554 |
| 3-vessel | 9 (9.9%) | 7 (7.3%) | 5 (10.0%) | 0.608 | 0.727 |
| SYNTAX score | 12.26±7.38 | 12.91±7.00 | 12.59±7.22 | 0.591 | 0.797 |
Data are expressed as mean±SD or as number (percentage). CAVD: calcific aortic valve disease; AVSc: aortic valve sclerosis; AVS: aortic valve stenosis. P 1: control group vs. patients with AVSc; P 2: patients with AVSc vs. those with AVS