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. Author manuscript; available in PMC: 2015 May 15.
Published in final edited form as: Am J Clin Pathol. 2010 Feb;133(2):265–270. doi: 10.1309/AJCPUS3PRRT5ZXVS

Image 1.

Image 1

Small lymphocyte–like plasma cell myeloma morphologic features. A, Bone marrow aspirate. The plasma cells are small with a scant rim of cytoplasm with an appearance similar to that of a mature lymphocyte (Wright, ×1,500). B, Bone marrow core biopsy specimen. Small lymphocyte–like plasma cells infiltrate the marrow in an interstitial and nodular pattern (H&E, ×300). C, Appearance of nodular focus at higher power. Small lymphocyte–like plasma cells demonstrate mature condensed chromatin and minimal cytoplasm (H&E, ×600). D, CD138 immunohistochemical staining (B-A38, Serotec, Oxford, England, 1:20 dilution, Benchmark automatic stainer with standard antigen retrieval). Diffuse CD138 immunohistochemical labeling of small lymphocyte–like plasma cells is present (×600).