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. 2015 May 15;10(5):e0126942. doi: 10.1371/journal.pone.0126942

Fig 10. A model summarizing our results.

Fig 10

In early brain corticogenesis, EphA4 in collaboration with FGFRs regulates transition through the neuronal lineage and accelerates self-renewal of RGCs. Black and gray arrows indicate the process of differentiation and self-renewal, respectively. Red arrow-headed lines indicate the function of acceleration and blue T-shaped lines indicate that of suppression. PAX6, TBR2, and TUBB3 are the markers for RGCs, INPs, and neuronal cells, respectively. Gray circles, RGCs; Green circle, committed RGCs; Green squares, INPs; Blue triangles, neuronal cells. CP, cortical plate; SVZ, subventricular zone; VZ, ventricular zone.