Table 1. List of variables.

TGF-β receptor-ligand	$R_{\mathrm{\text{ec}}}^{\star }(\varphi )$	{14.625, 28.364, 19.847, 16.888}
number of nearest neighbour cells with phenotype ϕ	ρ(ϕ, t)	$\{6,0,0,0\}[{V_{\mathrm{\text{neigh}}}}^{-1}]$
Circulating tumour cells	CTC	$\sim 0[{V_{\mathrm{\text{blood}}}}^{-1}]$
extravasating tumour cells	CTC e	$\sim 0[{V_{\mathrm{\text{blood}}}}^{-1}]$
Bisphosphonates concentration	BP	0 [mg ml−1]

If the variable depends on the phenotype ϕ, then we give a list of values sorted by increasing order of the phenotype. References and choices for the numerical values of the initial conditions are discussed in the Results section.