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. 2015 May 15;10(5):e0125481. doi: 10.1371/journal.pone.0125481

Fig 9. cSiO2 exposure elevates IgG (A), IgA (B), and IgM (C) concentrations in BALF of NZBWF1 and C57Bl/6 mice.

Fig 9

Total immunoglobulins in BALF were measured by ELISA. Data are group mean ± SEM (n = 7–8/gp) and were analyzed by one-way ANOVA on Ranks with Dunn’s method (NZBWF1) or Mann-Whitney Rank Sum Test (C57Bl/6). Asterisk indicates a statistically significant difference between cSiO2 treatment and vehicle control (p < 0.05). In BALF of NZBWF1 mice, cSiO2 dose correlated significantly (p < 0.05) with IgG (Spearman rank-order correlation coefficient = 0.80), IgA (Spearman rank-order correlation coefficient = 0.72), and IgM (Spearman rank-order correlation coefficient = 0.85).