Table 1. Baseline characteristics of 183 participants.
Variable | Mean (±SD) or number (%) |
Age (years) | 55± 15 |
Male | 105(57%) |
Diabetes mellitus | 52(28%) |
Hypertension | 165(90%) |
Smoking (current or former) | 92(51%) |
Hypercholesterolemia | 98(54%) |
Previous cardiovascular events | 82(45%) |
Body mass index (BMI) (kg/m2) | 27±5 |
Blood Pressure (BP) | |
Systolic BP (mmHg) | 145±22 |
Diastolic BP (mmHg) | 82±13 |
Causes of renal disease | |
Diabetic nephropathy | 41(22%) |
Chronic GN | 44(24%) |
Renovascular /hypertensive nephrosclerosis | 15(8%) |
Reflux nephropathy | 12(7%) |
Adult Polycystic Kidney Disease (ADPKD) | 18(10%) |
Others | 34(19%) |
Unknown | 19(10%) |
Renal factors | |
Stage 4/5 CKD (GFR<30ml/min) | 68(37%) |
Hemodialysis | 73(40%) |
Peritoneal Dialysis | 42(23%) |
Duration of dialysis (y)(median and IQR) | 1.8(0.5–4.0) |
Received Renal Transplant | 70(38%) |
Biochemistry | |
Corrected Calcium (mmol/L) | 2.4±0.2 |
Phosphate (mmol/L) | 1.8±0.5 |
Parathyroid Hormone (pmol/L) (median and IQR) | 30(14.5–59) |
Albumin(g/L) | 38±5.2 |
Hemoglobin(g/L) | 109±15 |
Medication | |
ACE inhibitor | 73(40%) |
Β —Blocker | 60(33%) |
Calcium channel blocker | 85(46%) |
Cholesterol lowering agent | 102(56%) |
Echocardiographic characteristics | |
LV end diastolic volume (mm) | 140± 48 |
LV end systolic volume (mm) | 79±37 |
LV mass index (g/m2.7) | 55±17 |
LV hypertrophy (LVMI > 51 g/m2.7) | 87(53%) |
LV meridional systolic wall stress (dynes/cm2x1000) | 149.8 ± 48.5 |
Ejection Fraction (%) | 45±11 |
Global Longitudinal Strain (%) | -13.6±4.3 |
SD = standard deviation; CKD = chronic kidney disease; LV = left ventricular; LVMI = left ventricular mass index; GN = glomerulonephritis; ACE = angiotensin converting enzyme