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. 2015 May 15;10(5):e0126726. doi: 10.1371/journal.pone.0126726

Fig 7. The effect of CRAds on the AKT signal pathway in TERT+EphA3+ tumor cells.

Fig 7

A: C4-2B cells were infected with Ad-TERTp-E1A-1504 and Ad-TERTp-E1A-NC (10 MOI) and 2 days after infection the AKT/mTOR pathway was detected by Western blot. p-mTOR, pAKT, and p4Ebp-1 were downregulated by Ad-TERTp-E1A-1504 compared with NC. B: HGC27 cells were infected with Ad-ΔE1-1504 and Ad-ΔE1-NC (400 MOI) and 2 days after infection the AKT/mTOR pathway was detected by Western blot. p-mTOR, pAKT, and p4Ebp-1 were downregulated by Ad-TERTp-E1A-1504 compared with NC.