Table 2.
Positive Hedonic Behaviors | Negative Affective Behaviors | ||||||
---|---|---|---|---|---|---|---|
Groups | LTP | PL | RTP | F | FW | G | HS |
SV | 0.33±0.33 | 12.50± 8.92 | 17.00±4.79 | 2.17±1.22 | 21.00±8.96 | 7.17±3.46 | 2.50±0.85 |
S2 | 3.83±1.40 | 3.83± 1.42 | 32.00±9.83 | 0.00±0.00 | 3.17±1.76 | 0.83±0.65 | 0.33±0.33 |
S4 | 0.50±0.34 | 11.83± 8.43 | 33.33±2.78 | 0.00±0.00 | 1.00±1.00 | 1.33±1.33 | 0.00±0.00 |
FV | 1.20±0.80 | 88.00±19.78 | 18.80±6.21 | 0.80±0.37 | 9.60±3.40 | 1.40±0.98 | 1.00±0.77 |
F2 | 5.50±2.14 | 21.67±11.22 | 28.83±8.73 | 0.17±0.17 | 0.67±0.33 | 5.00±3.33 | 0.33±0.33 |
F4 | 0.80±0.58 | 7.40± 2.94 | 43.00±7.31 | 0.00±0.00 | 0.00±0.00 | 0.80±0.49 | 0.60±0.24 |
Positive hedonic responses (mean±SEM) were subdivided into lateral tongue protrusions (LTP), paw licks (PL) and rhythmic (midline) tongue protrusions (RTP). Negative affective responses (mean±SEM) were subdivided into flails (F), face wipes (FW), gapes (G), and head shakes (HS). Experimental treatment groups: SV = sham depleted + vehicle; S2 = sham depleted + morphine (2 mg/kg); S4 = sham depleted + morphine (4 mg/kg); FV = furosemide depletion + vehicle; F2 = furosemide depletion + morphine (2 mg/kg); F4 = furosemide depletion + morphine (4 mg/kg).