Table 2.

Signs and symptoms reported in 18 patients with X-LAG syndrome at presentation

Sign/symptom	Number of patients (%)
Abnormally increased growth	18 (100)%
Acral enlargement	7 (38.9%)
Increased appetite	7 (38.9%)
Coarsened facial features	6 (33.3%)
Acanthosis nigricans	4 (22.2%)
Sleep apnea/ snoring	3 (16.7%)
Excessive perspiration/body odor	3 (16.7%)
Widening of interdental spaces	3 (16.7%)
Abdominal distension/weight gain	2 (11.1%)
Other (pubic hair, prognathism, ataxia, visual field defect, seizure, thickened skin, headache)	1 each (5.6%)