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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Hypertension. 2015 Apr 27;65(6):1349–1355. doi: 10.1161/HYPERTENSIONAHA.115.05344

Figure 4.

Figure 4

Inhibition of ER stress attenuated AngII-induced ADAM17 induction in VSMCs. A. Rat VSMCs were pretreated with or without PBA (1 – 10 mmol/L for 30 min) and were stimulated with AngII (100 nmol/L) for 18 h. The cell lysates were analyzed by immunoblotting as indicated (means ± SEM, n=4 in each group). B. Rat VSMC infected with adenovirus encoding GRP78 or control LacZ (100 moi) were stimulated with AngII (100 nmol/L) for 24 h. The cell lysates were analyzed by immunoblotting as indicated (means ± SEM, n=4 in each group). *p<0.05 compared with basal. †p<0.05 compared with AngII stimulation.