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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Mol Cancer Res. 2015 Jan 30;13(5):819–827. doi: 10.1158/1541-7786.MCR-14-0492

Figure 1. Structure model of OPG-TRAIL complex.

Figure 1

Superposition of human TRAIL (orange) with human RANKL (blue)-OPG (green) complex using a RANKL monomer as a reference (A); Surface diagram of TRAIL (orange) and OPG (green) (B); and, putative OPG residues (in green) interacting with TRAIL (C) are shown. Designated amino acid residues (Y49, N81, F96, and F107) were subjected to site-directed mutagenesis. Ribbon and surface diagrams were created with the PyMol program.