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. 2014 Jan 23;25(3):675–681. doi: 10.1093/annonc/mdt592

Table 4.

Study objectives for trials exclusively for the elderly

Trials exclusively for elderlya (%) All other trials (%) P-value
Toxicity 71 80 0.08
Efficacy 76 73 0.61
Progression-free survival 66 51 0.02
Overall survival 58 38 0.002
Biological parameters 10 29 0.001
Pharmacological parameters 15 20 0.31
Quality of life 18 7 0.002
Health care utilization 7 4 0.33
Completion of treatment 3 2 0.40
Functioning 2 0.7 0.42

aTrials were considered as exclusively for the elderly if they exclude patients aged 60 years of age or younger.