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MicroCT imaging of 5 month-old, female C57BL/6 (A), GATA-1low/low (B), OPG−/− (C), and GATA-1low/low X OPG−/− (D) mice. These images illustrate increased porosity observed in OPG deficient mice, which remained in mice deficient in both GATA-1 and OPG.