. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: J Cell Physiol. 2015 Apr;230(4):783–790. doi: 10.1002/jcp.24803

Table 1.

Trabecular Bone Properties in GATA-1^low/low X OPG^−/− and C57BL/6 Mice

		Micro CT					Histology

Mice	n	BV/TV (%)	BS/TV (1/mm)	Tb.Th (mm)	Tb.N (1/mm)	Tb.Sp (mm)	BV/TV (%)	N.Ob/T.Ar	N.Oc/T.Ar
C57BL/6	24	3.9±0.3^a,^b	3.8±0.2^a,^b	0.047±0.002^b	0.81±0.04^a,^b	0.303±0.004^b,^c	3.6±0.3^a	33±4^a,^b	24±2^a,^b
GATA-1 low/low	9	10.5±2.6^a,^d,^e	7.9±1.8^a,^d,^e	0.049±0.003^d	2.06±0.50^a,^d,^e	0.308±0.025^d,^e	14.1±2.7^a,^d,^e	86±11^a,^d,^e	53±5^a,^d,^e
OPG^−/−	6	0.4±0.2^b,^d	2.1±0.3^b,^d	0.033±0.005^b,^d,^f	0.13±0.06^b,^d	0.437±0.011^b,^d,^f	0.8±0.4^d	8±4^b,^d	8±4^b,^d
GATA-1 ^low/low X OPG^A	12	2.9±1.0^e	2.5±0.8^e	0.047±0.002^f	0.58±0.19^e	0.389±0.024^c,^e,^f	1.1±0.4^e	12±4^e	12±4^e

Abbreviations: BV/TV, bone volume/total volume; BS/TV, bone surface/total volume; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular spacing; N.Ob/T.Ar, number of osteoblasts/tissue area; N.Oc/T.Ar, number of osteoclasts/tissue area.

Results are presented as mean ± SEM

GATA-1^low/low, p < 0.05 compared with C57BL/6

OPG^−/−, p < 0.05 compared with C57BL/6

GATA-1^low/low x OPG^−/−, p < 0.05 compared with C57BL/6

OPG^−/−, p < 0.05 compared with GATA-1^low/low

GATA-1^low/low X OPG^−/− p < 0.05 compared with GATA-1^low/low

GATA-1^low/low X OPG^−/−, p < 0.05 compared with OPG^−/−