Table 3.

Mechanical and Biomaterial Properties in GATA-1^low/low X OPG^−/− and C57BL/6 Mice

Mice	n	Stiffness (N/mm)	Polar Moment of Inertia (mm4)	Ultimate Failure (MPa)	Load at Peak (N)	Modulus (GPa)	Toughness (MJ/m3)	Energy to Ultimate Force (mJ)
C57BL/6	24	129.7±3.6b,c	0.34±0.07a,b,c	244±5b,c	22.5±0.1a,b,c	47±1a,b,c	3.3±0.1c	9.9±0.3a,b,c
GATA-1low/low	9	135.3±6.7e	0.27±0.02a,e	269±45d,e	25.7±0.7a,d,e	58±3a,d,e	2.9±0.2	7.2±0.6a,d
OPG−/−	6	21.7±5.3b,d	0.25±0.02b,f	106±26b,d	9.6±0.7b,d	11±3b,d	2.7±0.8	4.6±1.2b,d
GATA-1low/low X OPG−/−	12	41.1±3.7c,e	0.46±0.06c,e,f	90±8c,e	6.6±1.1c,e	13±2c,e	1.9±0.3c	6.2±0.6c

Results are presented as mean ± SEM.

^aGATA-1^low/low, p < 0.05 compared with C57BL/6

^bOPG X OPG^−/−, p < 0.05 compared with C57BL/6

^cGATA-1^low/low x OPG^−/−, p < 0.05 compared with C57BL/6

^dOPG^−/−, p < 0.05 compared with GATA-1^low/low

^eGATA-1^low/low X OPG^−/−, p < 0.05 compared with GATA-1^low/,ow

^fGATA-1^low/low X OPG^−/−, p < 0.05 compared with OPG^−/−