Table 1.
CN n = 60 | DLB n = 30 | AD n = 30 | p-value* | |
---|---|---|---|---|
Females (%) | 10 (17) | 5 (17) | 5 (17) | 1.0 |
Age (y) | 68.5 (63, 76) | 69 (63, 76) | 72.5 (64, 79) | 0.48 |
Education (y) | 15.5 (12.5, 18) | 15 (12, 18) | 16 (12, 18) | 0.69 |
APOE ε4 carriers (%) | 11 (18) | 13 (43) | 23 (77) | <0.001 |
CDR sum of boxes | 0.0 (0.0, 0.0) | 5.75 (4.0, 7.0) | 4.75 (2.5, 7.0) | <0.001 |
MMSE | 29 (28, 29) | 20.5 (15, 24) | 21 (14, 23) | <0.001 |
DRS | - | 125.5 (114, 131) | 111 (85, 127) | 0.03 |
PiB SUVR | 1.31 (1.27, 1.37) | 1.43 (1.30, 1.88) | 2.35 (2.17, 2.52) | <0.001 |
VH present (%) | - | 23 (77) | 2 (8) | <0.001 |
Fluctuations present (%) | - | 27 (90) | 2 (8) | <0.001 |
Motor UPDRS | - | 12 (7, 14) | 0 (0, 2) | <0.001 |
RBD present (%) | - | 28 (93) | 4 (15) | <0.001 |
Dementia duration (y) | - | 5.04 (3.75, 7.17) | 5.21 (3.50, 7.00) | 0.88 |
VH duration (y) | - | 1.91 (0.75, 3.59) | - | - |
Fluctuations duration (y) | - | 2.25 (1.49, 3.67) | - | - |
Parkinsonism duration (y) | - | 3.50 (1.17, 5.75) | - | - |
RBD duration (y) | - | 9.21 (4.16, 14.08) | - | - |
Medians (IQR) are listed for the continuous and the proportions (%) are for the categorical variables.
p-values are from the Wilcoxon rank sum for the continuous variables, and a χ2 test for differences in proportions. VH = visual hallucinations (probable and definite combined together). RBD = probable REM-sleep behavior disorder, SUVR=Standardized uptake value ratio.