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Effects of early postnatal treatment with the VPAC2 receptor agonist Ro 25-1553 on open-field behavior determined at three to four months of age. Each mouse was placed individually into a clear Plexiglas chamber (27.5 cm × 27.5 cm × 20.5 cm) and the behavior was recorded for 20 min. The distance traveled in the peripheral and center area and the time spent in the center area are calculated. The results are expressed as the mean ± SEM of 8 mice/group.
