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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Psychopharmacology (Berl). 2015 Jan 11;232(12):2181–2189. doi: 10.1007/s00213-014-3848-z

Fig. 4.

Fig. 4

Effects of early postnatal treatment with the VPAC2 receptor agonist Ro 25-1553 development on performance in the three-chamber social interaction test. After habituation, a mouse was placed in the central chamber of a clear Plexiglas box (41 cm × 60 cm × 23.5 cm) divided into three interconnected chambers and was given the choice to interact with either an empty wire cup (Empty) or a similar wire cup with an unfamiliar mouse (Stranger). The amount of time spent in each of the three chambers was recorded for the test mouse in a 10-min. The results are expressed as the mean ± SEM of 8 mice/group. **P < 0.01 compared with the middle chamber. ††P < 0.01 compared with the empty side.