Table 1.

Gene Ontology cellular compartment analysis.

Annotations	Proteins	NGR	Hyp	Hyp∗
GO:0005737: cytoplasm	1106	5302	1.8 × 10−289	1.3 × 10−286
GO:0005634: nucleus	803	5441	1.2 × 10−101	2.14 × 10−99
GO:0005829: cytosol	633	2146	4.4 × 10−234	1.6 × 10−231
GO:0016020: membrane	551	4065	1.2 × 10−52	9.2 × 10−51
GO:0005886: plasma membrane	472	3575	3.1 × 10−41	1.4 × 10−39
GO:0005739: mitochondrion	453	1394	1.8 × 10−181	4.3 × 10−179
GO:0016021: integral to membrane	405	4400	6.1 × 10−8	5.2 × 10−7
GO:0005730: nucleolus	320	1461	6.2 × 10−76	8.8 × 10−74
GO:0005622: intracellular	230	1962	8.8 × 10−14	1.6 × 10−12
GO:0005783: endoplasmic reticulum	222	1000	2.8 × 10−53	2.5 × 10−51
GO:0005654: nucleoplasm	215	891	4.3 × 10−58	4.36 × 10−56
GO:0005856: cytoskeleton	187	846	1.4 × 10−44	8.4 × 10−43
GO:0005794: Golgi apparatus	174	958	3.5 × 10−30	1.2 × 10−28
GO:0005576: extracellular region	170	1913	0.003	0.008
GO:0005789: endoplasmic reticulum membrane	140	642	7.3 × 10−33	2.7 × 10−31
GO:0005625: soluble fraction	120	390	4.1 × 10−44	2.2 × 10−42
GO:0048471: perinuclear region of cytoplasm	115	417	3.3 × 10−37	1.4 × 10−35
GO:0005743: mitochondrial inner membrane	113	308	2.8 × 10−50	2.0 × 10−48
GO:0005759: mitochondrial matrix	104	201	3.3 × 10−64	3.9 × 10−62
GO:0005624: membrane fraction	98	523	2.0 × 10−18	5.0 × 10−42
GO:0005615: extracellular space	96	784	2.5 × 10−7	2.1 × 10−6
GO:0005887: integral to plasma membrane	94	1016	0.008	0.02
GO:0030054: cell junction	85	475	5.9 × 10−15	1.1 × 10−13
GO:0005840: ribosome	78	174	1.5 × 10−42	7.1 × 10−41
GO:0000139: Golgi membrane	75	420	2.6 × 10−13	4.4 × 10−12
GO:0045202: synapse	70	288	8.86 × 10−20	2.4 × 10−18
GO:0030529: ribonucleoprotein complex	69	132	2.2 × 10−43	1.1 × 10−41
GO:0031410: cytoplasmic vesicle	67	287	5.2 × 10−18	1.3 × 10−16
GO:0005792: microsome	64	279	7.3 × 10−17	1.6 × 10−15
GO:0005813: centrosome	63	323	3.7 × 10−13	6.1 × 10−12
GO:0042470: melanosome	59	89	1.1 × 10−45	7.0 × 10−44
GO:0005874: microtubule	59	262	2.8 × 10−15	5.7 × 10−14
GO:0009986: cell surface	57	297	9.6 × 10−12	1.3 × 10−10
GO:0043231: intracellular membrane-bounded organelle	56	269	4.7 × 10−13	7.4 × 10−12
GO:0015629: actin cytoskeleton	54	180	5.16 × 10−20	1.52 × 10−18
GO:0043234: protein complex	53	217	2.0 × 10−15	4.0 × 10−14
GO:0043025: neuronal cell body	48	217	2.1 × 10−12	3.2 × 10−11
GO:0005694: chromosome	48	265	3.0 × 10−9	3.3 × 10−8
GO:0071013: catalytic step 2 spliceosome	47	79	1.8 × 10−33	7.1 × 10−32
GO:0016607: nuclear speck	46	134	6.8 × 10−20	1.9 × 10−18
GO:0005768: endosome	45	280	3.5 × 10−7	2.6 × 10−6
GO:0030424: axon	43	173	4.6 × 10−13	7.3 × 10−12
GO:0030425: dendrite	42	182	1.2 × 10−11	1.5 × 10−20
GO:0005764: lysosome	40	179	1.0 × 10−10	1.2 × 10−9
GO:0019717: synaptosome	39	111	1.7 × 10−17	4.1 × 10−16
GO:0042995: cell projection	39	158	6.9 × 10−12	9.8 × 10−11
GO:0022625: cytosolic large ribosomal subunit	38	52	1.9 × 10−32	6.9 × 10−31
GO:0005741: mitochondrial outer membrane	37	102	3.4 × 10−17	7.8 × 10−16
GO:0031012: extracellular matrix	37	146	1.0 × 10−11	1.3 × 10−11
GO:0000502: proteasome complex	36	60	3.8 × 10−26	1.2 × 10−24
GO:0016323: basolateral plasma membrane	35	129	4.4 × 10−12	6.4 × 10−11
GO:0005681: spliceosomal complex	34	75	1.6 × 10−19	4.1 × 10−18
GO:0016324: apical plasma membrane	32	196	1.2 × 10−5	6.4 × 10−5
GO:0005938: cell cortex	31	106	8.7 × 10−12	1.2 × 10−10
GO:0005635: nuclear envelope	31	107	1.1 × 10−11	1.5 × 10−10
GO:0031965: nuclear membrane	30	133	1.7 × 10−8	1.6 × 10−7
GO:0005911: cell-cell junction	29	93	6.9 × 10−12	9.6 × 10−11
GO:0005788: endoplasmic reticulum lumen	29	106	2.4 × 10−10	2.8 × 10−9
GO:0005925: focal adhesion	28	116	1.0 × 10−8	1.1 × 10−7
GO:0030496: midbody	27	73	3.6 × 10−13	6.0 × 10−12
GO:0005769: early endosome	27	122	1.3 × 10−7	1.1 × 10−6
GO:0022627: cytosolic small ribosomal subunit	26	36	2.2 × 10−22	6.8 × 10−21
GO:0015630: microtubule cytoskeleton	26	97	3.2 × 10−9	3.4 × 10−8
GO:0045211: postsynaptic membrane	26	170	0.0002	0.0009
GO:0005643: nuclear pore	25	58	4.1 × 10−14	7.7 × 10−13
GO:0045121: membrane raft	25	128	4.3 × 10−6	2.5 × 10−5
GO:0009897: external side of plasma membrane	25	155	0.0001	0.0005
GO:0008021: synaptic vesicle	24	70	4.7 × 10−11	5.7 × 10−10
GO:0005777: peroxisome	24	105	3.4 × 10−7	2.6 × 10−11
GO:0014069: postsynaptic density	23	107	1.9 × 10−6	1.2 × 10−5
GO:0005793: endoplasmic reticulum-Golgi intermediate compartment	22	46	9.8 × 10−14	1.7 × 10−12
GO:0005819: spindle	22	113	1.7 × 10−5	8.9 × 10−5
GO:0005765: lysosomal membrane	22	123	6.4 × 10−5	0.0003
GO:0010008: endosome membrane	22	145	0.0007	0.003
GO:0001725: stress fiber	21	45	6.6 × 10−13	1.0 × 10−11
GO:0030426: growth cone	21	72	2.0 × 10−8	1.9 × 10−7
GO:0043005: neuron projection	21	81	1.9 × 10−7	1.6 × 10−6
GO:0005905: coated pit	20	46	1.2 × 10−11	1.5 × 10−10
GO:0031901: early endosome membrane	20	63	8.7 × 10−7	9.07 × 10−8
GO:0001726: ruffle	20	72	1.1 × 10−7	9.2 × 10−7
GO:0030659: cytoplasmic vesicle membrane	20	83	1.3 × 10−6	8.9 × 10−6
GO:0030027: lamellipodium	20	101	3.0 × 10−5	0.0002

Cellular compartments identified by at least 20 proteins are included.

Proteins: number of proteins identified in cellular compartment.

NGR: number of annotated proteins in the reference list.

Hyp: hypergeometric p value.

Hyp^∗: corrected hypergeometric p value.