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. 2015 May 3;2015:192415. doi: 10.1155/2015/192415

Figure 1.

Figure 1

Complement synovial infiltration in the early pathogenesis of OA. ELISA quantification of C3a des-arginine in synovial fluid of healthy (n = 14), early-stage OA (n = 52), and end-stage OA (n = 69) patients. C3a des-arginine is a carboxypeptidase-cleaved, stable form of C3a that is generated from C3 during activation of the complement cascade. ** P ≤ 0.01 by one-way analysis of variance (ANOVA) and Dunnett's post hoc test (reproduction of image with permission and modified caption from Wang et al. [17]).