Table 3.
Probes for mediators of inflammation in modern imaging techniques.
| Cell type or protein | Probe |
|---|---|
| Macrophage | (i) 18F-FDG (PET) [98, 99] |
|
| |
| CD4+ T cell | (i) 64Cu-PTSM (PET) [100] (ii) 18F-FB-IL-2 (PET) [99] |
|
| |
| B cell | (i) 124I-rituximab (PET) [101] |
|
| |
| Neutrophil | (i) cFLFLF-PEG-Cy 7 (NIRF) (ii) cFLFLF-PEG-DOTA-64Cu (PET) |
|
| |
| Mast cell | (i) Ligand 1 (in vitro) [102] |
|
| |
| TNFα | (i) 64Cu-DOTA-etanercept (PET) [103] |
|
| |
| Complement | (i) USPIO-conjugated anti-C3mab (T2-MRI) [104] |
|
| |
| MMP | (i) 124I-HO-MPI (CGS 27023A) (PET) [105] |