Table 5.
REML estimation of thrombolytic drugs data: Wald χ2 statistics testing consistency, selected estimated treatment effects and their standard errors, comparing standard approach with data augmentation approach for various choices of h and m and the reference treatment
Data augmentation approach | |||||||||
---|---|---|---|---|---|---|---|---|---|
Standard approach | Reference treatment | m | 0.08 | 0.5 | |||||
h | 0.001 | 0.01 | 0.1 | 0.001 | 0.01 | 0.1 | |||
Wald test of consistency ![]() |
8.61 | A | 8.61 | 8.61 | 8.60 | 8.60 | 8.59 | 8.42 | |
B | 8.61 | 8.61 | 8.62 | 8.61 | 8.62 | 8.64 | |||
C | 8.61 | 8.61 | 8.60 | 8.60 | 8.59 | 8.35 | |||
Treatment effect δAB | −0.161 | A | −0.161 | −0.161 | −0.161 | −0.161 | −0.161 | −0.162 | |
B | −0.161 | −0.161 | −0.161 | −0.161 | −0.161 | −0.158 | |||
C | −0.161 | −0.161 | −0.161 | −0.161 | −0.161 | −0.162 | |||
Treatment effect δAG | −0.197 | A | −0.197 | −0.197 | −0.197 | −0.197 | −0.198 | −0.205 | |
B | −0.197 | −0.197 | −0.198 | −0.197 | −0.198 | −0.202 | |||
C | −0.197 | −0.197 | −0.197 | −0.197 | −0.198 | −0.202 | |||
Standard error se(δAB) | 0.046 | A | 0.046 | 0.046 | 0.046 | 0.046 | 0.046 | 0.046 | |
B | 0.046 | 0.046 | 0.046 | 0.046 | 0.046 | 0.046 | |||
C | 0.046 | 0.046 | 0.046 | 0.046 | 0.046 | 0.047 | |||
Standard error se(δAG) | 0.222 | A | 0.222 | 0.222 | 0.222 | 0.222 | 0.222 | 0.221 | |
B | 0.222 | 0.222 | 0.222 | 0.222 | 0.222 | 0.221 | |||
C | 0.222 | 0.222 | 0.222 | 0.222 | 0.222 | 0.221 |