Figure 5. IFN-β reduces numbers of GM-CSF only CD4+ and CD8+ T cells.
PBMCs from healthy donors (n=15) and MS patients (untreated MS n=13; IFN-β treated n=9) were stimulated with anti-CD3/anti-CD28 Abs in the presence or absence of IFN-β. Percentages of GM-CSF+IFN-γ+ and GM-CSF only CD4+ and CD8+ T cells in total CD4+ and CD8+ cells are shown. * p<0.05, ** p<0.01, *** p<0.001, NS: not significant (Paired, two-tailed Student t-test).
