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. Author manuscript; available in PMC: 2016 Jul 28.
Published in final edited form as: Cancer Lett. 2015 Apr 24;363(2):166–175. doi: 10.1016/j.canlet.2015.04.017

Fig. 3.

Fig. 3

FLLL12 induces DR5-mediated apoptosis. (A) A549, H1299 and H292 cells were treated with FLLL12 and curcumin for 24 h and the expression of DR5 protein was determined by Western blotting. (B) A549 cells were transfected with control (siC) and DR5 (siDR5) siRNA as described in the Materials and methods and apoptosis was quantified after 24 h of FLLL12 treatment. (C) A549 cells were transfected and treated with FLLL12 as in (B). Expression of DR5, cleaved caspase-3 and PARP were analyzed by Western blotting.