Figure 1.
Effect of LTC4 on eosinophilic pulmonary inflammation and platelet activation. OVA-sensitized C57BL/6 were challenged with 0.1% OVA on three successive days, with or without inhalation of LTC4 (2.2 nmol) 12 h before each challenge. BAL fluid was collected 24 h after the last OVA challenge. A. Total cell counts, total eosinophils, and percentage of eosinophils and in BAL fluids. B. Levels of TXB2 in BAL fluid lipid fractions. C. Levels of BAL fluid CXCL7. Results in A-C are from ten mice/group from two separate experiments. * p<0.05, *** p<0.001.