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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Immunol. 2015 Apr 22;194(11):5061–5068. doi: 10.4049/jimmunol.1402959

Figure 4.

Figure 4

LTC4-mediated upregulation of pulmonary ICAM-1 and VCAM-1 proteins. Lysates were prepared from whole lung of the indicated strains of sensitized mice obtained 24 h after challenge with OVA with or without LTC4. Some mice received aspirin in their drinking water. A. Western blots showing ICAM-1, VCAM-1, and GAPDH from the lungs of representative mice. B. Quantitative densitometry from the lungs of 5 mice/group. C. Immunohistochemical stains of lungs of representative OVA-sensitized mice challenged with low dose OVA either with vehicle or with LTC4. * p<0.05, ** p<0.01.