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. Author manuscript; available in PMC: 2016 Jun 19.
Published in final edited form as: J Mol Biol. 2015 Apr 18;427(12):2229–2243. doi: 10.1016/j.jmb.2015.04.008

Fig. 1. Chemical structures of lincosamides and aminoglycosides inactivated by O-nucleotidyltransferase enzymes.

Fig. 1

A) Chemical structure of lincosamides. B) Chemical structure of kanamycin B, a representative 4,6-disubstituted 2-deoxystreptamine aminoglycoside. The O-nucleotidylation sites and nucleotidylylation product on both antibiotic classes are indicated with arrows and labelled by catalyzing enzyme family.