Table 3.
Representative top structural homologs of Lnu(A)
| PDB IDa | Protein name | Z-score | RMSD (# Cα atoms) | % identity |
|---|---|---|---|---|
| 4WQK | ANT(2″)-Ia | 16.2 | 2.3 (145) | 18 |
| 2FCL | T. maritima hypothetical protein TM1012 | 12.3 | 3.3 (157) | 15 |
| 4OK0 | H. pylori putative NT JHP933 | 9.3 | 2.8 (125) | 16 |
| 3UQ0 | (euk.)b DNA pol λ | 7.7 | 3.2 (101) | 12 |
| 4F5Q | (euk.) DNA pol β | 7.6 | 3.9 (105) | 10 |
| 4NKT | (euk.) poly (U) polymerase | 7.3 | 3.9 (100) | 12 |
| 1UEV | (arch.) CCA-adding enzyme | 7.0 | 4.4 (118) | 7 |
| 4M04 | (euk.) DNA poly μ | 6.8 | 3.9 (103) | 13 |
| 4K99 | (euk.) cGMP-AMP synthase | 6.5 | 4.4 (116) | 8 |
| 3NYB | (euk.) pola (A) RNA polymerase | 6.4 | 3.4 (86) | 8 |
| 3JZ0 | E. faecium Lnu(B) | 6.4 | 3.7 (107) | 11 |
| 1JMS | (euk.) terminal DNA NT | 6.3 | 4.0 (106) | 10 |
| 4ATB | (euk.) NF90 | 5.9 | 4.7 (114) | 7 |
| 1MIV | B. stearothermophilus CCA-adding enzyme | 5.9 | 3.8 (113) | 12 |
| 2NRK | E. faecalis GrpB | 5.7 | 4.0 (94) | 10 |
| 1ZEL | M. tuberculosis RV2827C | 5.4 | 3.7 (105) | 13 |
| 1NO5 | H. pylori HI0073 NT | 3.5 | 4.8 (102) | 11 |
| 2PBE | B. subtilis predicted ANT(6)-Ia | 4.4 | 3.2 (88) | 9 |
| 3L9D | S. mutans Smu.1046C | 4.1 | 3.6 (94) | 6 |
| 4EBK | ANT(4′)-IIb | 3.6 | 4.2 (78) | 9 |
| 1KNY | ANT(4′)-Ia | 3.1 | 3.6 (73) | 12 |
a
multiple PDB IDs of the same protein were often retrieved; indicated stats are from those PDB IDs with the highest Z-score).
b
euk. = eukaryotic; arch. = archeal.