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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Mar 31;1852(7):1323–1333. doi: 10.1016/j.bbadis.2015.03.010

Figure 10. Obesity induced podocyte apoptosis were attenuated in CD36 KO mice.

Figure 10

Male CD36 −/− mice at eight weeks of age and age-matched wild type littermate controls were fed a low fat (10% kcal as fat) or a high fat diet (60% kcal as fat) for 16 weeks. After that, mice were harvested and kidney tissues were collected. Apoptotic cell number was calculated after tunel staining (A). The scale bar represents 50 µm. In addition, glomerular caspase 3 protein expression (B) and caspase 3 activity (C) were determined by using immunochemical staining and caspase-3 colorimetric assay kit, respectively. Data are presented as mean ± SE (n = 6 mice/group). *, P <0.05 vs. WT/lean group; #, P <0.05 vs. WT/obese group.