Table 3.

Genotype and allelic frequencies of –308G/A TNF-α polymorphism among patients with different stages of CRC.

–308G/A polymorphism in TNF-α gene
	GG	GA	AA	Allele-G	Allele-A
CRC stage	n (%)	n (%)	n (%)	n (%)	n (%)
Stage I (n = 14)	9 (64%)	5 (36%)	–	23 (82%)	5 (18%)
Stage II (n = 44)	33 (75%)	9 (20.5%)	2 (4.5%)	75 (85%)	13 (15%)
Stage III (n = 43)	34 (79%)	9 (54%)	–	77 (89.5%)	9 (10.5%)
Stage IV (n = 18)	12 (67%)	5 (28%)	1 (5%)	29 (81%)	7 (19%)
Early CRC – Stages I and II (n = 58)	42 (72.4%)	14 (24.2%)	2 (3.4%)	98 (84.5%)	18 (15.5%)
Advanced CRC – Stages III and IV (n = 61)	46 (75%)	14 (23%)	1 (2%)	106 (87%)	16 (13%)