Table 1.
Allele and genotype frequencies of the MMP2 −1306C>T SNP in the studied Caucasian population compared to other populations.
| Minor allele frequency (MAF) |
Genotype number and frequencies |
|||||
|---|---|---|---|---|---|---|
| Country/populations | p-value | C/C N (%) | C/T N (%) | T/T N (%) | p-value | |
| Central Bulgaria/Caucasians (our study) | 16.2 | 53 (74.6) | 13 (18.3) | 5 (7.0) | ||
| Sweden/Caucasians [26] | 26.2 | 0.021 | 109 (52.4) | 89 (42.8) | 10 (4.8) | 0.002 |
| Texas, USA/Caucasians [27] | 24.2 | 0.043 | 312 (57.2) | 202 (37.1) | 31 (5.7) | 0.012 |
| The Netherlands/Caucasians [28] | 26.9 | 0.007 | 609 (52.8) | 466 (40.5) | 77 (6.7) | 0.001 |
| China/Asians [29] | 14.3 | 0.609 | 92 (73.0) | 32 (25.5) | 2 (1.6) | 0.208 |
| China/Asians [22] | 11.8 | 0.132 | 487 (78.0) | 3137 (21.0) | 6 (1.0) | 0.003 |
| Thailand [13] | 12.8 | 0.297 | 190 (76.0) | 56 (22.4) | 4 (1.6) | 0.115 |
| Austria/Caucasians [30] | 26.6 | 0.011 | 138 (55.6) | 88 (35.5) | 22 (8.9) | 0.021 |
| Turkey/Caucasians [24] | 9.2 | 0.026 | 142 (81.6) | 32 (18.4) | 0 (0) | 0.010 |
| Global genotype distribution [25] | 14.0 | 0.813 | (75.3) | (21.3) | (3.4) | 0.686 |