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. 2015 May 15;6(4):662–672. doi: 10.4239/wjd.v6.i4.662

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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.

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Receptor of advanced glycation end products immune-staining in villi (A, C, E) and crypt (B, D, F) of duodenum (A, B), jejunum (C, D) and ileum(E, F) as well as in ileum ganglia (arrowhead; G: Normal group; H: GK group). As shown in the magnification area (big frame vs small frame), the RAGE homogeneously distributed in the epithelia cells. The intensity of immune-staining in ganglia was stronger in the diabetic group (H) than in the normal group (G) (arrowhead). RAGE: Receptor of advanced glycation end products; GK: Inherited type 2 diabetic Goto-Kakizak rats.