Table 1.
Summary of nine case reports of brain metastasis from USC.
| Case 1 |
Case 2 |
Case 3 |
Case 4 |
Case 5 |
Case 6 |
Case 7 |
Case 8 |
Case 9 |
|
|---|---|---|---|---|---|---|---|---|---|
| Petru 2001 | Gien 2003 | Gien 2003 | Dietrich 2005 | Chura 2007 | Comert 2012 | Talwar 2012 | Gulsen 2013 | Sinai 2013 | |
| Age at diagnosis of metastasis | 60 | 72 | 82 | 72 | 63 | Unknown | 68 | 71 | 55 |
| Stage | Unstaged | IIIC | IIB | IC | IA | IB | IA | Unknown | IIIC2 |
| Grade | 3 | Unknown | Unknown | Unknown | 3 | 3 | 3 | Unknown | 3 |
| LVSI | + | + | − | Unknown | Unknown | Unknown | − | Unknown | + |
| Depth of myometrial invasion | “Deep, serosal involvement” | > 50% | > 50% | > 50% | < 50% | > 50% | 0% | Unknown | > 50% |
| Interval (months) between primary diagnosis & brain metastasis | N/A* | 40 | 24 | 22 | 0.6 | 2 | > 60 | 27 | 11 |
| Number of brain metastases | Solitary | Multiple | Multiple | Unknown | Unknown | Solitary | Unknown | Multiple | Solitary |
| Systemic disease | None | Lung | Vault | Liver, lung | None | “Disseminated abdominal spread” | Lung | Unknown | None |
| Lesion location | R cerebellum | Cerebellum, L temporal | R frontal, R temporal, R parietal, bioccipital | Unknown | Unknown | Unknown | Unknown | Posterior fossa, R frontal lobe | Bifrontal tumor |
| Surgical excision | + | − | − | − | + | − | − | + | + |
| Brain metastasis treatment | Radiosurgery, chemotherapy, medroxyprogesterone | WBRT | Steroids | Unknown | WBRT, chemotherapy | Unknown | WBRT, chemotherapy | WBRT, chemotherapy | WBRT, chemotherapy |
| Brain metastasis survival (months) | 15 | 5 | 0.25 | 2 | 9.2 | 5 | > 3 | > 9 | Alive with disease, > 12 |